New York Times book description: What we call Alzheimer's disease is actually a protective response to a wide variety of insults to the brain: inflammation, insulin resistance, toxins, infections, and inadequate levels of nutrients, hormones, and growth factors. Bredesen starts by having us figure out which of these insults we need to address and continues by laying out a personalized lifestyle plan. Focusing on the Ketoflex 12/3 Diet, which triggers ketosis and lets the brain restore itself with a minimum 12-hour fast, Dr. Bredesen drills down on restorative sleep, targeted supplementation, exercise, and brain training. He also examines the tricky question of toxic exposure and provides workarounds for many difficult problems. The takeaway is that we do not need to do the program perfectly but will see tremendous results if we can do it well enough.
‘Simple illnesses such as pneumonia versus complex illnesses such as Alzheimer’s. Simple illnesses may have many contributors, but a single one is far and away the dominant, and therefore a single drug, like penicillin, is often curative. In contrast, complex illnesses may have many contributors, but no single contributor is the clear dominant, and therefore identifying and addressing multiple contributors with a precision protocol is the most effective approach to treatment.’
Page 7, The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age, Dale Bredesen M.D. with foreword by David Perimutter M.D.